NŪYŪ Daily NMN™ Longevity Drink-Tropical Peach Mango

After NAD+ returns to healthy levels, ongoing supplementation will keep those levels high.

It is recommened to be taken 1-2 times daily.  Follow the specific directions printed on each product for the recommended daily dosage. 

Most customers notice a boost in energy after only using a few uses. Other benefits become noticeable over the next 7-10 days.

NMN, or Nicotinamide Mononucleotide, is a derivative of Vitamin B3, also known as niacin, and it is part of the pathway involved in the synthesis of NAD (Nicotinamide Adenine Dinucleotide).  NMN is a precursor molecule in the biosynthesis of NAD, which is a critical coenzyme involved in various cellular processes, including energy metabolism and DNA repair. The conversion of NMN to NAD occurs through a series of enzymatic reactions in the cell. One key enzyme involved in this process is NMN adenylyltransferase (NMNAT), which catalyzes the conversion of NMN to NAD by adding an adenylyl group to NMN. This reaction results in the formation of NAD.  Both NMN and NR have gained attention for their potential anti-aging properties, primarily because they can increase NAD levels in cells, which is believed to be beneficial for various aspects of aging.  NAD plays a crucial role in aging-related processes primarily through its involvement in cellular energy production and DNA repair. Some key aspects of NAD's role in aging include: Energy Production: NAD is a coenzyme that participates in cellular respiration and the production of adenosine triphosphate (ATP), the cell's primary energy currency. As we age, NAD levels tend to decline, leading to reduced cellular energy production and overall vitality.DNA Repair: NAD is essential for DNA repair enzymes called sirtuins, which help maintain genomic stability. As NAD levels decrease with age, DNA repair processes become less efficient, potentially contributing to age-related DNA damage.

Resveratrol and pterostilbene are both naturally occurring plant compounds. Resveratrol is concentrated in grape skins and red wine, but it has also been isolated from the roots of Japanese knotweed. Pterostilbene is concentrated primarily in blueberries, but it has also been found in small amounts in peanuts, grapes and cocoa. Although many biological similarities exist between pterostilbene and resveratrol, pterostilbene shows better bioactivity and bioavailability. Resveratrol supports cardiovascular health, antioxidant defenses, glucose metabolism, healthy inflammatory balance, and more. Pterostilbene is now championed as a more potent form with superior bioavailability.

Sirtuins are a family of proteins (SIRT1-7) that play a crucial role in regulating cellular processes related to aging and longevity. They are involved in gene expression, DNA repair, stress response, and metabolic control.

Sirtuins are involved in various aspects of aging, including:Longevity: Sirtuins are linked to increased lifespan in various organisms, including yeast, worms, flies, and mice. Activating sirtuins can promote longevity.Metabolism: Sirtuins play a role in regulating metabolism, including glucose and lipid metabolism, which can impact age-related diseases like diabetes and obesity.DNA Repair: Sirtuins are involved in DNA repair processes, helping to maintain genomic stability and reduce the accumulation of DNA damage that occurs with aging.

Several compounds can activate sirtuins including Resveratrol, Pterostilbene, and both NMN and NR. Resveratrol is a natural polyphenol found in grapes and red wine. It is known to activate SIRT1, a sirtuin associated with various aspects of aging, including metabolism and DNA repair. Pterostilbene is another polyphenol, similar to resveratrol, found in certain berries and grapes. It can also activate SIRT1. Both NMN and NR can increase cellular NAD levels. This increase in NAD can indirectly activate sirtuins, particularly SIRT1, by providing them with the necessary coenzyme.

Calcium AKG (Alpha-Ketoglutarate) is a compound that combines calcium with alpha-ketoglutaric acid. It is often used as a dietary supplement. Calcium AKG has potential implications for various aspects of health, including aging, and bone health. Calcium AKG has been used as a potential anti-aging compound due to its role in cellular energy production. Alpha-ketoglutarate is a key intermediate in the citric acid cycle, a process that generates ATP, the body's primary energy source. As we age, cellular energy production can decline, and some research shows that calcium AKG could help improve energy metabolism and, consequently, slow down the aging process. Combining calcium with alpha-ketoglutarate in the form of calcium AKG may enhance the absorption of calcium in the body. Adequate calcium intake is necessary for maintaining strong bones and preventing conditions like osteoporosis.

Homocysteine is an amino acid that is a natural byproduct of the metabolism of another amino acid called methionine. It is typically present in the body, but elevated levels of homocysteine in the blood are associated with several health problems, including cardiovascular disease and have been linked to mood, anxiety, and depression. Some studies suggest a potential link between high homocysteine levels and these mental health conditions. High homocysteine levels can lead to increased oxidative stress and inflammation in the body, which are factors that have been linked to depressive symptoms. Elevated homocysteine levels can disrupt the balance of neurotransmitters in the brain, such as serotonin and dopamine. These neurotransmitters play a crucial role in mood regulation, and imbalances can contribute to mood disorders. Elevated homocysteine levels have also been associated with cognitive decline and an increased risk of conditions like dementia and Alzheimer's disease. Cognitive impairment and mood disorders are often interconnected.  
The regulation of homocysteine levels in the body is influenced by various factors, including B vitamins and TMG (Trimethylglycine). Several B vitamins, including vitamin B6 (pyridoxine), vitamin B9 (folate or folic acid), and vitamin B12 (cobalamin), play a crucial role in regulating homocysteine levels. Folate (Vitamin B9) Folate is necessary for the conversion of homocysteine into methionine. Without adequate folate, homocysteine cannot be metabolized effectively, leading to its accumulation in the blood. Vitamin B12 is also required for the conversion of homocysteine to methionine. A deficiency in B12 can impair this process, leading to elevated homocysteine levels. Vitamin B6 is involved in the transsulfuration pathway, which helps convert homocysteine into cysteine or recycle it into methionine. Adequate vitamin B6 levels are essential for this conversion. TMG (Trimethylglycine) is another important regulator of homocysteine levels. TMG donates a methyl group, which is essential for converting homocysteine into methionine. It aids in the remethylation of homocysteine, reducing its concentration in the blood.

Citrulline malate is a compound consisting of the amino acid citrulline and malic acid. It is often used as a dietary supplement and is associated with several potential health benefits, including its relation to aging, energy, and cardiovascular health. As we age, there is a natural decline in energy levels and physical performance. Citrulline malate has been studied for its potential to increase energy and endurance. By enhancing the production of nitric oxide (NO), it may help improve blood flow and oxygen delivery to tissues, potentially providing a modest boost in energy and exercise performance.  Citrulline malate is often used by athletes and individuals seeking to improve their physical performance. It is believed to enhance exercise capacity by reducing muscle fatigue and increasing ATP (adenosine triphosphate) production, which is the primary energy currency of cells. This effect on energy production can be valuable in the context of physical activity and exercise. It also may play a role in cardiovascular health through its ability to increase nitric oxide production. Nitric oxide helps relax blood vessels, which can lead to improved blood flow and reduced blood pressure. This vasodilation effect may contribute to better cardiovascular health.

Vitamin B5, B6, B9, and B12 are essential B vitamins that play various roles in the body, including contributing to overall health and potentially impacting the aging process and the health of the skin, hair, and nails.  Vitamin B5 (Pantothenic Acid) is involved in skin health and has been used in skincare products. It may help maintain skin moisture and promote wound healing. B5 is also thought to contribute to healthy hair and nail growth. Vitamin B6 (Pyridoxine) is important for skin health, as it is involved in the formation of collagen, which is crucial for skin elasticity and repair. Adequate B6 is also necessary for healthy hair and nails.  Vitamin B9 (Folate or Folic Acid): plays a role in DNA synthesis and repair, which is important for healthy cell turnover and tissue repair. Adequate folate intake is necessary for maintaining overall health and can support healthy aging. Folate may be involved in skin health through its role in DNA synthesis, helping to maintain and repair skin cells Additionally, folate is thought to support healthy hair and nail growth. Vitamin B12 (Cobalamin) is necessary for maintaining the health of the nervous system, and it is essential for energy production. As people age, B12 absorption can decrease, potentially leading to issues like anemia, fatigue, and neurological problems. B12 may have an indirect role in skin health by promoting overall well-being and energy. B12 supplements can support healthy hair and nail growth, especially if a deficiency is present.

NŪYŪ Daily NMN™ also contains Vitamin C, Vitamin D3, and Vitamin K2-MK7.  These vitamins are important for overall health and can support healthy aging by helping to maintain strong bones, a well-functioning immune system, and skin elasticity. Vitamin C is essential for the production of collagen, a protein that provides structural support to the skin, joints, and blood vessels. Collagen production decreases with age, and adequate vitamin C intake can help support skin elasticity and joint health. Vitamin C is a potent antioxidant that helps protect cells from oxidative stress and damage. This can be beneficial for overall health, as oxidative stress is a factor in the aging process. Vitamin C also supports the immune system, which can help maintain health as the body ages. It aids in the production of white blood cells and strengthens the body's defenses against infections. Vitamin D3 plays a crucial role in calcium absorption, which is vital for bone health. As people age, maintaining strong bones becomes increasingly important to prevent conditions like osteoporosis.It has also been linked to immune system support, and adequate levels are important for immune function. A well-functioning immune system is crucial for overall health, especially as people age. Vitamin K2-MK7 is particularly associated with bone health. It helps regulate calcium metabolism, ensuring that calcium is directed to the bones and teeth rather than accumulating in soft tissues or arteries. This can help prevent age-related conditions like osteoporosis. It may also play a role in cardiovascular health by preventing calcium buildup in arterial walls. Cardiovascular health is an important aspect of aging well.

Yes. There are adequate levels of Collagen Peptides, Vitamins C, D, B5, B6, B9, B12, and Calcium to replace those supplements.

In addition to the various health benefits, NŪYŪ is a delicious daily alternative alternative to combat aging from the inside out.  No needles, no downtime, no pills, just a once or twice daily longevity drink in various, exciting flavors to help people Look Better, Feel Better, and Live More.

All ingredients in NŪYŪ Daily NMN™ are GRAS (Generally Recognized As Safe) by the FDA under sections 201(s) and 409 of the Federal Food, Drug, and Cosmetic Act (the Act). When taking NMN for the first time, some users may experience a mild upset stomach. Though NŪYŪ Daily NMN™ can be taken with or without food, if you experience this, it is recommended that you take it with food. Symptoms generally subside with more usage.

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